Management of cerebral venous sinus thrombosis

David Goldemund M.D.
Updated on 21/03/2024, published on 13/03/2024

  • cerebral venous sinus thrombosis (CVST) is a potentially life-threatening condition that demands prompt diagnosis and appropriate management to reduce associated morbidity and mortality
  • if CVST is suspected, imaging modalities such as MR imaging and MR or CT venography can help confirm the diagnosis  → Diagnosis of CVST
    • CT is widely available and is the most commonly used baseline imaging modality, although MRI with venous TOF sequence is preferred for its better sensitivity
    • CT is widely used as a baseline imaging modality, but MRI with venous TOF sequence is preferred due to its better sensitivity
  • once the diagnosis is established, general therapy and acute anticoagulation should be initiated
    • the objectives of anticoagulation therapy in CVST are to:
      • prevent thrombus growth
      • facilitate spontaneous fibrinolytic activity
      • prevent recurrent VTE events
    • general therapy focuses on the management of complications (seizure, venous infarction, etc.) and symptoms (headache, vomitus, etc.)
  • detect and treat the cause of thrombosis, if possible
  • endovascular treatment or surgery should be reserved for extensive or progressive thrombosis

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Management of cerebral venous sinus thrombosis
link: https://www.stroke-manual.com/management-of-cerebral-venous-sinus-thrombosis/