Blend sign

Created 25/02/2022, last revision 18/01/2023

  • early hematoma growth occurs in approximately one-third of the patients with spontaneous intracerebral hemorrhage (ICH)
  • the blend sign (BS) on baseline NCCT is a marker of increased risk of hemorrhage progression and a predictor of poor outcome in patients with ICH  Blend sign predicts poor prognosis in ICH patients (Li, 2017)   [Li, 2017]
  • there is a good correlation with the spot sign, which is more sensitive and reliable but requires the use of a contrast agent  [Sporns, 2017]
  • blend sign and black hole sign can help predict outcome when CTA is not available
Blend sign specifications
  • a mix of hyperdense and relatively hypodense areas (difference > 18 HU)
  • well distinguishable by eye
  • sharply demarcated from each other
  • the hypodense area is not completely surrounded by the hyperdense area
Blend sign
Blend sign
Blend sign (baseline and 3hr later)

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Blend Sign