Blend sign

Created 25/02/2022, last revision 05/04/2022

  • early hematoma growth occurs in approximately one-third of the patients with spontaneous intracerebral hemorrhage (ICH)
  • blend sign (BS) found on baseline NCCT is a marker of increased risk of bleeding progression and predictor of poor outcome in patients with ICH Blend sign predicts poor prognosis in ICH patients (Li, 2017)   [Li, 2017]
  • there is a good correlation with the spot sign, which is more sensitive and reliable but requires the application of a contrast agent  [Sporns, 2017]
  • blend sign and black hole sign can be helpful in predicting outcome if CTA is not available
Blend sign specifications
  • mix of hyperdense and relatively hypodense areas (difference > 18 HU)
  • well distinguishable by eye
  • sharply demarcated from each other
  • hypodense area is not completely surrounded by the hyperdense area
Blend sign
Blend sign
Blend sign (baseline and 3hr later)
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