Varicella zoster virus vasculopathy

Ohthalmic herpes zoster
ISCHEMIC STROKE / CLASSIFICATION AND ETIOPATHOGENESIS Varicella-zoster virus vasculopathy David Goldemund M.D.Updated on 21/02/2024, published on 20/02/2024 [toc] varicella-zoster virus (VZV) is a neurotropic herpesvirus responsible for two distinct clinical conditions: varicella (primary infection) and herpes zoster (reactivation) while the cutaneous manifestation is a well-known aspect of VZV infection, the virus also harbors the potential ... Read more

Behcet disease

Ulcerations and skin lesions in Behcet disease
ISCHEMIC STROKE / CLASSIFICATION AND ETIOPATOGENESIS Behçet disease David Goldemund M.D.Updated on 22/02/2024, published on 16/02/2024 [toc] Behçet disease is characterized by the inflammation of blood vessels (vasculitis) of multiple organ systems etiology remains unclear;  genetic predisposition (HLA-B51), environmental factors, and immune system dysregulation are thought to be involved usual onset between 20-30 years of ... Read more

Central retinal artery occlusion (CRAO)

Cherry red spot and pale retina in CRAO
ADD-ONS / OTHER VASCULAR DISORDERS Central retinal artery occlusion (CRAO) David Goldemund M.D.Updated on 21/03/2024, published on 01/02/2024 [toc] AHA guidelines 2021 - Management of CRA occlusion Ocular vascular disorders Ocular vascular disorders Ischemic optic neuropathy (ION) anterior (AION) arteritic non-arteritic posterior (PION) Central retinal vein occlusion (CRVO) → more (the most common retinal vascular ... Read more

Transient ischemic attack (TIA)

Express trial
ISCHEMIC STROKE Transient ischemic attack (TIA) David Goldemund M.D.Updated on 20/03/2024, published on 29/12/2023 [toc] 2021 ESO guidelines on the management of transient ischemic attack (TIA) Transient Ischemic Attack (TIA) is a medical emergency despite its seemingly mild course, TIA is a serious predictor of subsequent ischemic stroke and death following TIA, the risk of ... Read more

Diagnosis of intracerebral hemorrhage

Blend sign (baseline and 3hr later)
INTRACEREBRAL HEMORRHAGE Diagnosis of intracerebral hemorrhage David Goldemund M.D.Updated on 07/03/2024, published on 27/11/2023 [toc] for patients presenting with stroke-like symptoms, rapid neuroimaging using CT or MRI is recommended to confirm the diagnosis of spontaneous intracerebral hemorrhage (ICH) the detection of intracerebral bleeding itself by imaging methods is easy; the diagnostic evaluation is focused on ... Read more

Rostrocaudal deterioration

Brainstem death - all brainstem reflexes are absent
GENERAL NEUROLOGY Rostrocaudal deterioration David Goldemund M.D.Updated on 25/11/2023, published on 18/11/2023 disorders of consciousness are caused by dysfunction of the ascending reticular activating system (ARAS) in the brainstem, its impaired connections with the cerebral cortex (reticulo-cortical pathways), or generalized cerebral dysfunction  dysfunction in these areas can result in a spectrum of impaired consciousness, ranging ... Read more

Statin intolerance

Statin intolerance
ADD-ONS / MEDICATION Statin intolerance David Goldemund M.D.Updated on 18/11/2023, published on 14/11/2023 [toc] NLA scientific statement on statin intolerance: a new definition and key considerations for ASCVD risk reduction in the statin intolerant patient Abbreviations: ULN = upper limit of normal. CK = creatine kinase , LDL = low density lipoprotein, SAMS = statin ... Read more

Statins and their interactions

ISCHEMIC STROKE / PREVENTION Statins and their interactions David Goldemund M.D.Updated on 18/03/2024, published on 19/10/2023 [toc] statins are competitive HMG-CoA reductase inhibitors  that are effective in stroke prevention interactions of statins with other drugs affect their metabolism and can be clinically serious; they may be responsible for up to nearly 60% of statin-related myopathy/rhabdomyolysis ... Read more

Lipid-lowering therapy

Lipid-lowering drugs
ISCHEMIC STROKE / PREVENTION Lipid-lowering therapy David Goldemund M.D.Updated on 21/03/2024, published on 18/10/2023 [toc] 2019 - ESC/EAS Guidelines for the Management of Dyslipidaemias dyslipidemia is a major modifiable vascular risk factor treatment with lipid-lowering drugs (hypolipidemics) reduces the incidence of ischemic stroke and other atherosclerotic cardiovascular events (ASCVD) hypolipidemics (and their combinations) help to ... Read more

Posterior Reversible Encephalopathy Syndrome (PRES)

PRES - MRI baseline and follow-up
OTHER VASCULAR DISORDERS Posterior Reversible Encephalopathy Syndrome (PRES) David Goldemund M.D.Updated on 15/03/2024, published on 23/09/2023 [toc] clinical-radiologic syndrome sometimes called reversible posterior leukoencephalopathy syndrome ( RPLS) or acute hypertensive encephalopathy the name may be misleading: pathologic changes may extend beyond the posterior regions some patients may develop permanent brain damage with neurological deficits diagnosis ... Read more

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