Cerebral amyloid angiopathy (CAA)

Cerebral amyloid angiopathy with repeated lobar hematomas
CEREBRAL HEMORRHAGE Cerebral amyloid angiopathy (CAA) David Goldemund M.D.Updated on 22/04/2024, published on 13/04/2023 [toc] a heterogeneous group of sporadic or familial disorders characterized by deposition of amyloid beta-peptide (Aβ) in the walls of small to medium-sized cerebral and leptomeningeal vessels in the absence of systemic amyloidosis sporadic form - affects mainly the elderly population ... Read more

Apnea test for brain death diagnosis

Apnea test for brain death diagnosis
ADD-ONS Apnea test for brain death diagnosis David Goldemund M.D.Updated on 02/02/2024, published on 11/04/2023 [toc] Why the apnea test is performed brain death (BD) is defined as the irreversible cessation of all brain functions (including those of the brainstem) the apnea test is a mandatory examination for determining brain death, serving as an essential ... Read more

Brain death diagnosis

Cerebral circulatory arrest on DSA
ADD-ONS Brain death diagnosis David Goldemund M.D.Updated on 25/04/2024, published on 10/04/2023 [toc] Brain death definition brain death (BD) is defined as the irreversible loss of all brain functions (including the brainstem), regardless of the continued function of the cardiovascular system and other organs Etiology traumatic brain injury (TBI) stroke global cerebral hypoxia/anoxia (post-CPR conditions) ... Read more

Management of subarachnoid hemorrhage

Aneurysm clipping, artifact from the clip on CT scan
SUBARACHNOID HEMORRHAGE Management of subarachnoid hemorrhage David Goldemund M.D.Updated on 14/03/2024, published on 01/04/2023 [toc] Standard management of SAH focuses on: blood pressure control and maintenance of normovolemia prevention and treatment of vasospasms elimination of the aneurysm from the circulation prevention and management of complications  (both intra- and extracerebral) General therapy and patient monitoring the initial ... Read more

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Management in the subacute phase of cerebral venous thrombosis

Hyperdense sign on NCCT (left), CT venography with defective contrast filling of the right transverse and sigmoid sinuses
CEREBRAL VENOUS SINUS THROMBOSIS Management in the subacute phase of cerebral venous thrombosis David Goldemund M.D.Updated on 21/03/2024, published on 08/03/2023 [toc] Anticoagulant therapy Drug choice acute parenteral therapy (usually using LMWH) is switched to oral anticoagulant therapy after 5-15 days (AHA guidelines, 2024) WARFARIN with a target INR 2-3  → see here DOACs  seem ... Read more

Dyslipidemia

Xanthelasma
ISCHEMIC STROKE / PREVENTION Dyslipidemia David Goldemund M.D.Updated on 12/04/2024, published on 20/02/2023 [toc] 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk Definition of dyslipidemia the previously used term hyperlipidemia is now replaced by the broader term dyslipoproteinemia or dyslipidemia (DLP), which better reflects the fact that the pathology ... Read more

Arterial hypertension

Manual aneroid manometer
ISCHEMIC STROKE / PREVENTION / RISK FACTORS Arterial hypertension David Goldemund M.D.Updated on 21/11/2023, published on 20/02/2023 [toc] 2022 - WHO guideline for the pharmacological treatment of hypertension in adults 2018 - ESC/ESH Guidelines for the management of arterial hypertension Definition of hypertension hypertension is defined as office SBP values ≥ 140 mmHg and/or diastolic ... Read more

Diabetes mellitus

Diabetes mellitus
ISCHEMIC STROKE / PREVENTION / RISK FACTORS Diabetes mellitus David Goldemund M.D.Updated on 05/02/2024, published on 20/02/2023 [toc] Definition diabetes is a syndrome characterized by the inability of the body to process glucose and maintain its levels within physiological limits due to absolute (↓ secretion) or relative insulin deficiency (↑ resistance), resulting in altered glycide, ... Read more

Smoking

Smoking
ISCHEMIC STROKE / PREVENTION Smoking David Goldemund M.D.Updated on 05/02/2024, published on 20/02/2023 [toc] Smoking and risk of stroke smoking is classified as a disease (dg. F17 - drug addiction) cigarette smoking and passive smoking are both significant independent risk factors for ischemic stroke (1.5-2 fold risk)  [Peters, 2013] the excess risk of stroke is ... Read more

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